The A24 has been closed between the A27 in Worthing and the A280 in Findon after a serious crash.
A number of vehicles including a bus and a motorbike have been involved in a collision at the junction of Findon Road and Allendale Avenue in Worthing shortly before 4.00 pm today (Monday June 1st).
Police, fire and ambulance crews are at the scene.
The road could remain closed for a number of hours.
Anyone with information should email: firstname.lastname@example.org or call 101 quoting Operation Redtail.